We would both agree with you.
The nightmare pre-jab compared with post jab. And we knew a number of people who died from Covid - inc my hairdresser, 5 days after cutting my hair!
The point is that if these are AEs associated with vaccines, you would see an established pattern in a broad population⊠and it will be reported as such, even if no causation link is established, any issues post taking a new medicine are reported through strict pharmacovigilance procedure in all countries⊠Ironically, new medicines are often initially considered to have worse safety profiles than in reality as every ailment no matter what the real cause is included in the reported AE events.
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Letâs face it.
The only reason there are any questions being asked are because Boris so closely associated himself with the programmes
Sort of linked to Covid
I go in to the office in The City 1-2 times a week and it seems Tues, Weds and Thurs are the new Thurs - pubs are really busy. Trains and tube starting to get rammed as well.
The TWaT crowd as theyâre known at my place
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Exactly - Iâm a fully paid up member!
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I go into the City office almost never. Rammed trains and ticket costs can go do one 
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Why are they worried about getting FDA approval if itâs safe?
I know a few of the city trader / broker types through work - they are particularly scathing of the Twats.
I wonder how keen the twats will be to remain twats, if their twatish behaviour means that they lose out on career progression to the non-twats
Another outbreak at Mrs P_Fâs office just confirmed today
She is now convinced she & MiL had it again last week but she thought at the time it was a stress headache from the muppets at work.
How you feeling @Goatboy?
Me?
WhateverâŠ
Iâm fine apart from being in the UK.
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You can fly to the Philppines
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Need to first correct the insinuation in that video, that Pfizer were giving more info to shareholders than clinicians. This is utter bollocks. They have released all the clinical data they have available to them to date, and this is what is used both by the FDA. EMA , HMRC etc to approve the products and this data is available to all clinicians and if you want to read it , its in the public domain.
Clinicians can either follow the national guidelines or review the data themselves to be as informed as possible on the clinical benefit versus risk ratio as with all new medicines. What they are not concerned about is any commercial implications
What is also a legal requirement is that shareholders are informed accurately about new drugs from a commercial standpoint to avoid misinformation misleading investors. The biggest investors in pharma co are institutional/ pension funds etc and they want stable sustainable growth, not highly volatile share prices based on misleading information.
The word âworriedâ is not appropriate. Itâs an emotive word and is not used by Pfizer, its someones deliberate choice of word as it suggest concern, which is not the case. They are merely stating the obvious to anyone who knows how long clinical evaluations take and that its never straight forward or guaranteed, so they are legally obliged to conclude that investors must be aware that they may not be granted full approval, as they would with ANY medicine or vaccine granted conditional or accelerated approval.
With any medicine developed so rapidly, only conditional or emergency use will be granted initially. A lot can happen in the years that sit between this approval and being granted full approval- efficacy could be shown to wain, new strains could dominate so that this vaccine is no longer effective/useful, and yes there is a very small risk of adverse events being seen later that are not known today⊠BUT no more than for any other medicine granted such early approval, and it will be no different for every other COVID vaccine manufacturerâŠ
Are the COVID vaccines safe? Based on all the available evidence to date, YES. Is there a possibility of more as yet unknown side effects being presented in the future? YES, but its a very small risk since the technology of these and other vaccines is well understood. Does this tiny risk warrant not being vaccinated, NO. The risk of having COVID and having a serious event despite being very small in most age groups, is still MUCH HIGHER than any potential AE. (especially as vaccines are not just about protecting individuals, but about protecting the population - you get vaccinated, you are less of a risk as a spreader)
I suggest those concerned about risks of AEs etc, read the original peer reviewed papers (Lancet and NEJM) - and look at this with an unbiased POV, and get some neutral help with the stats - Compare the presentation of the AEs with a papers covering medicines they are familiar with such as Paracetamol, then also combine this with a bit of knowledge on established epidemiological principles⊠then make up you own minds⊠but AVOID these shitty misinforming nut job social media produced shite as they are directly responsible for deaths IMHO⊠as they misinform yet influence.
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Iâm less interested in what they told whom and more interested that theyâve listed the approval of the drug as a financial risk to their shareholders. If the data theyâve submitted to the FDA correlates with that, great, but itâs not my area of concern.
In the case of my âboosterâ, the clinician didnât have a choice. It was Pfizer or nothing for a patient they were previously saying should only have the AZ (when the AZ was available). By the time of the booster shot, Pfizer was the only thing going for miles around me.
Didnât get the âboosterâ because of that.
Long term data will bear it out, but it would be a gigantic shame if AZ were found to be less deadly and was disappeared off the shelves for commercial consideration.
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But that is same for ALL drugs with accelerated approval - will be same for AZ, nothing out of ordinary
It can not be any different - if they really had let shareholder have access to data that was not in public domain/submitted to FDA - they would currently be facing a 50billion fine or more
This is NHS/Government decision based on availability of vaccines doses - its not right, but has fuck all to do with Pfizer safety. Seriously, if there as an increased risk associated with you having the Pfizer Booster vs there AZ then you would NOT have been offered the Pfizer, subject to medical history⊠I have family members who were also initially told AZ is best for you because of underlying conditions, but only if there was a choice, since both are effective and safe by the evaluation standards - The differences in risk based patient profiles are tinyâŠ
Not sure of the point here? Medicines dont stop being available unless they are shown to be ineffective or have poor safety profiles and something better comes along⊠I will predict that all that current vaccines will be replaced by new ones, longer term single dose ones or annual cocktails dependent on predicted dominant strains as with the flu vaccines will become the norm.
You cant blame manufacturers for government procurement choices (eventually this will go back to NICE when no longer an emergency pandemic) What will be available to UK folks is what NICE evaluates as the best options (cost effectiveness will pay a part) - but this has nothing to do with how companies report to shareholders
I would add, that I am no big fan of global pharma cos, all have done naughty things and have faced huge fines because of it, but having read and digested so much on COVID from peer reviewed sources, I feel in this case, the benefits and lives saved massively outweighs the very small risks associated with these vaccines. The evidence for both a societal benefit and individual benefit is just overwhelming
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I agree with everything here.
@pap I would urge you to get the booster. It does give enhanced protection from the currently circulating virus variants.
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Iâll have one when itâs offered to my age group. Lady Slowlane and I havenât had Covid so we donât have the acquired natural immunity. It would be stupid to turn down the offer.
Nah, Iâm good.
Iâm quite weird in that I never really get ill. Havenât had a headache since I was fourteen.
Getting permanently maimed is more my speed.
You are lucky⊠I know someone who has COPD at age 49 from smoking for 30+year⊠and when they get flu, they are often laid up for 2 weeks an on one occasion broke 3 ribs due to coughing as they got pneumoniaâŠ
When they caught COVID, poor bastard was on a ventilator⊠thankfully survived, but was touch and go. He believes he caught it from his brother who⊠was unvaccinated, never showed any symptoms yet subsequently tested positive.
Vaccination is the real âsocialistâ of medicine. Its never about just the risk benefit ratio for the individual, but about the benefit to your community and society.
Even a vaccine that is 50% effective can get the R number down to under 1, if enough folks take it⊠it saves lives. There really is no reason for anyone to be worried about these vaccines.
If you are healthy and never get it, then you are MORE likely to be a symptomless carrier⊠its your choice not to have boosters etc, but then at least continue to wear a mask in public, not just around old people, as you never know which younger folks are immunocompromisedâŠ
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