When I was given the number to call to get my vaccine others did share it in WhatsApp groups. My partner asked if it would cover him (he works in another borough) only once Iād checked at the vaccine centre did I give him the number.
The MIL and FIL couldnāt get their vaccine today in Hampshire due to snow.
Dunno. Doesnāt invalidate the query people are asking about those contracting the virus after vaccination.
You know my position on this. I hope it works, but Iām concerned about the speed at which this has been brought to market, concerned about the scope of the programme.
This question is the #1 question of anyone advocating wait and see.
Iāve read that many places can produce a vaccine quickly but a lot of bureaucracy makes things take years instead. Pretty sure someone has mentioned that before on the thread.
Life is not risk free. Iām unhappy about not having the 2nd dose at 3 weeks and essentially becoming a guinea-pig but hopefully if I do get it (and none of the vaccine can 100% say you will not) then I am much happier to have lesser symptoms. There are some people getting the 1st dose who do go into hospital afterwards. Mainly very elderly. It seems having caught it just before or in the 3 weeks after when you are not covered from the jab.
Yep thatās whatās happened to my cousinā¦she was in hospital for 5 days then tested positive having had the jab 10 days before. Whoās to say whether she caught it in hospital or elsewhere. The immune system of the elderly is slower to respond.
re: speed to market concerns.
What has been cut out is the waiting time for the endless ethics/review/funding committees and patient recruitment delays that are part of the normal process. Plus stages have been done āat riskā i.e the next stage has been started before the decision from the review committee. A similar number of patients were in the clinical trial and the scrutiny was the same - just done at high priority.
The way things work in the immune system for other vaccines that we have more data about is that delaying the 2nd or booster shot results in a stronger response.
It is important to recognise that the immune system does not get cranked up immediately on vaccination. There is no difference between vaccinated and un-vaccinated people testing positive in the first 14 days. The rates only begin to diverge from day 14, so behave like you are unvaccinated for the first 3 weeks after your jab.
So, er, scrutiny then?
Done as standard, but on top priority. Normally a new drug/vaccine would have to take its place in the queue. This went straight to the head of the queue.
My question though, is if someone has Sinopharm this year & a mutant strain sees a modified jab needed can they then have a Pfzier or Astra next season?
Normally new drugs arenāt given to the entirety of the population. We donāt really advertise drugs here like they do in the US, but I always found it fascinating that the proportion of the ad explaining potential side effects is about 70% of the ad.
Back to my point, Iād like to know:-
Those are fair questions given the scale of this thing.
I am not an immunologist or virologist, but by my understanding there would be no problem with doing that.
I donāt think I can answer all those points as I donāt have the numbers, but with regard to the severity of symptons as @lifeintheslowlane said above, there were no hospitalisations among the vaccinated group. I think Dr John Campbell will have addressed these points in one of his YouTube presentations.
edit - maybe this one https://www.youtube.com/watch?v=M-jqf6i5OLc
In my profession, anytime we put something new live, we monitor the hell out of it. We look for things going wrong, for unanticipated side effects. Iām just someone that writes software.
Iāve not really worked in any other field, but I do know that verification tends to be big in all of them. We know that in general, vaccines work by allowing our own immune systems to tackle and defeat a smaller or similar infection. I donāt know the details of each of these vaccines, but if their production is predicated on that principle, itās important to know whether the balance is right.
Hereās more information on the two main vaccines on offer. The Pfizer is new tech, the Oxford a tried and trusted tech: https://theconversation.com/the-oxford-vaccine-has-unique-advantages-as-does-pfizers-using-both-is-australias-best-strategy-152976 both have gone through ALL the normal testing processes.
Dr. John Campbellās briefing today has some good information on post-vaccination behaviours. If youāre stuck for time most in the first 10 minutesā¦
There will be significant number of Real World Evidence (RWE) studies that are designed to do exactly that: record the efficacy and safety under real world conditions to see how these compare to the numbers obtained during clinical study conditions. I would hope they will also record and analyse differences that may be observed between the variable time delays to the second dose, but this will depend on the monitoring protocols in any RWE study or registries
Absolutely shocking, really sobering reading. The way those workers have been treated is absolutely shameful, it wouldnāt have been out of place in Dickensian times. Quite apart from the obvious contempt shown to the rest of the population, forcing people into work when they are showing symptoms, making them switch off their test and trace apps, not allowing vulnerable workers to work from home, and then sending them all out to mix with the rest of us. Absences relating to Covid being counted against their sick leave? People going in even when sick because they are scared of getting the sack if they donāt? A culture of fear? This is 2021 FFS, in the middle of a pandemic, absolutely fucking scandalous, and it shames the country.
This is Britannia Unchained in action, plenty more where this came from, this is what āTaking back controlā looks like in all itās glory. We canāt say we werenāt warned.
Our friend has been up a bit more today and managed to eat dinner - however runs out of energy really quickly and beats a retreat to bed pretty regularly