Oxford/AZ vaccine is just over Ā£2.20 a shot according to the Daily Fail
1 Like
I donāt know what the cost of the Oxford vaccine will be, but it is considerably cheaper than the Pfizer one. The Eu procurement scheme, which we shunned, secured a price of 15.50 euros per dose for 40 million doses of the Pfizer vaccine, the UK secured a price of 29.40. Which should surprise nobody really, in any trade negotiations the bigger and more powerful you are, the more clout you have and the better deal you get. This rule also applies applies to Brexit of course, just why Brexit supporters believe it doesnāt is beyond me. I suspect they will will be in for a rude shock in the coming months and years.
Oh bugger!
Be interesting to see a link to these figures as everything Iāve seen say that Pfizer are selling at not for profit āas long as the pandemic continuesā, so that means it should be the same cost for everyone. Every article Iāve read says about Ā£15 a dose, as 2 doses are required that ties up with the ~Ā£30 you quote the UK paidā¦
Another one for the Plague Rat badge?
2 Likes
I think the Oxford vaccine is a not for profit. Pfizers - not so much.
2 Likes
They talk about the revenue ie doses x unit price, there is not mention of profit margins
Now I have no idea what the relevant unit costs are, but i can imagine that a drug that needs -80c storage has a more temperamental production process and is therefore more costly
1 Like
And, I would imagine they had to bung huge R&D & testing budgets at it as well
Anywhere between 300m and 1bn to bring a drug to market - varies by disease typeā¦ but price is not just to cover cost of the drugs that make it, but the huge R&D costs of Those that donāt as well with many more failing at Phase 2 studiesā¦ the price of a drug is never just about cost of goods, manufacture and logistics if that drugā¦
3 Likes
Totally agree.
Also sometimes you can get a lot of R&D done free by, for example, a University
100% this.
3 Likes
Most of the questions youāve been asking have been answered by Dr. Johnā¦
2 Likes
Tell me about it. 1 new compound in 10k is successful. This is what I do it seems, make all the drug candidates that donāt get taken forward.
2 Likes
I feel your painā¦ although from the other sideā¦ 25 years in agency/consulting, now focussed on regulatory and market access consulting.
The ādiscoveryā costs are often only a very small percentage of the clinical development costs which are dominated by clinical study costs. Logistics, monitoring, legal, insurance etc all fees often delivered by CROs on behalf of the manufacturer (Clinical Research organisations). Universities are often involved in discover of new molecular entities but as Waylander says, there are very few that make it to approvalā¦The industry gets a bad press, but think about how many cancers full
Remission rates have gone up dramatically in the last 30-40 yearsā¦
1 Like
Universities are often involved in elucidating the biological processes that enable drug discovery, sometimes this is funded by pharma. The actual synthesis and establishment of the structure/activity relationship of the chemical series are more typically done by pharma labs (like mine).
2 Likes
Yep.
Equally, they often dont help themselves with differential pricing levels.
Like everything in a universe dominated by cost/profit, they must maximise.
Until so.eone invents Star Trek style replicates it will always be that way
Yep, my daughter is at med school doing something cancer related research-wise and there seems to be a fair bit of collaboration with Big Pharma.
Contacts in the pharma industry suggests sheād make more money in the pharma industry but lack of security if what youāre working on gets binned - have no idea if thatās true or not. Sheās young and idealistic so not too fussed at the moā
So they can screw up everything canāt they?
So I have my first dose the other week due to spare capacity. All good. Bit of an achy arm. Felt a bit weird but then that may have been stress from dad in hospital. I still havenāt been taken over by Gates nor a second head has grown for those of you waiting for us guinea pigs who go first.
Due next one, next weekend but that may not happen now. Iāve seen some health staff have theirs cancelled and it mentions social care shouldnāt go to their appointment.
I know I will be coming across biased here but the monumental task of cancelling 500000 odd appointments mostly for elderly people is going to be quite a task. There is no suggestion for the Pfizer one that this is safe. At this rate we may have to be re-vaccinated because 12 weeks is too much between doses thus wasting more money.
This should not have been retrospective for those already vaccinated. Appointments should be kept (apparently there is the ability to do this) and then they can start new regime. This should not have been agreed for pfizer one either by the looks of it over 42 days between doses hasnāt been assessed.
Iām pretty ready to stand outside downing street with a placard and protest this monumentally inept, lying, corrupt government. Anyone with me?
3 Likes
Iām still in Covid quarantine unfortunately 
But with you in thought 
2 Likes
If you can get me back to the UK I will hold your placard .
1 Like